4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid

4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid - Names and Identifiers

Name	4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid
Synonyms	BOC-4,4-ACP(1-N-FMOC) 4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid N-BOC-AMINO-(4-N-FMOC-PIPERIDINYL) CARBOXYLIC ACID 4-N-BOC-AMINO-(N-FMOC-PIPERDINYL)-4-CARBOXYLIC ACID 4-(Boc-amino)-1-(Fmoc-piperidinyl)-4-carboxylic Acid 4-N-Boc-amino-(N-Fmoc-piperidinyl)-4-carboxylic acid N-(TERT-BUTOXYCARBONYL)-AMINO-(4-N-FMOC-PIPERIDINYL)CARBOXYLIC ACID 4-TERT-BUTOXYCARBONYLAMINO-PIPERIDINE-1,4-DICARBOXYLIC ACID MONO-(9H-FLUOREN-9-YLMETHYL) ESTER 4-[(TERT-BUTOXYCARBONYL)AMINO]-1-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]PIPERIDINE-4-CARBOXYLIC ACID 1,4-Piperidinedicarboxylicacid,4-[[(1,1-dimethylethoxy)carbonyl]amino]-,1-(9H-fluoren-9-ylmethyl)ester(9CI)
CAS	368866-07-3

4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid - Physico-chemical Properties

Molecular Formula	C26H30N2O6
Molar Mass	466.53
Density	1.2464 (rough estimate)
Boling Point	569.36°C (rough estimate)
pKa	3.85±0.20(Predicted)
Storage Condition	Sealed in dry,2-8°C
Refractive Index	1.5300 (estimate)

4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S37/39 - Wear suitable gloves and eye/face protection S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
HS Code	29225090

4-(Boc-amino)-1-Fmoc-piperdine-4-carboxylic Acid - Introduction

4-(Boc-amino)-Acid(4-(Boc-amino)-Acid) is an organic compound containing a piperidine ring and a fluorene ring in its structure. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: White crystalline solid.
-Molecular weight: about 473.48g/mol.
-Melting point: about 135-139°C.
-Solubility: Soluble in some organic solvents, such as dimethyl sulfoxide, dimethylformamide and acetonitrile.

Use:
-Chemical synthesis: 4-(Boc-amino)-Acid is often used as an important intermediate in organic synthesis. For example, in drug synthesis, it can be used to synthesize peptides, drugs and bioactive molecules.
-protecting group: Boc and Fmoc groups are often used as protecting groups for amino groups to protect the reactivity of amino groups.

Preparation Method:
4-(Boc-amino)-The preparation method of Acid is more complicated and involves multi-step reactions. The following is a common preparation method:
1. synthesis of Boc-protected piperidine by chemical reaction.
2. The Boc-protected piperidine is reacted with Fmoc-Cl to generate 4-(Boc-amino)-1-Fmoc-piperdine.
3. Finally, 4-(Boc-amino)-1-Fmoc-piperdine is reacted with an appropriate acid to remove the Boc protecting group to obtain 4-(Boc-amino)-piperidine Acid.

Safety Information:
4-(Boc-amino)-The Acid is generally safe under correct use and storage. However, it is a chemical, and it is still necessary to follow the safe handling of chemicals, such as wearing appropriate personal protective equipment, avoiding contact with skin and eyes, and maintaining a well-ventilated working environment. In addition, the compound may have a certain stimulating effect on the human body, so it should be used with caution.

Last Update：2024-04-09 21:00:56